The evidence

Every benefit,validated by science.

Behind each onely pillar, independent, published and verifiable clinical studies. The actives are selected for their level of evidence and dosed at their effective amount.
Illustration of the clinical study on Rhodiola

Rhodiola

Description

In this randomized, double-blind, placebo-controlled trial, students under exam stress took 100 mg of standardized Rhodiola rosea extract once a day for 20 days.

Résultats

100 mg/day of Rhodiola Rosea reduced perceived fatigue and improved well-being during a stressful period compared to placebo.

-42% fatigue
-30% stress
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Vitamins and minerals

Description

This meta-analysis of eight randomized placebo-controlled trials in healthy adults showed that supplementation with vitamins and minerals for at least 28 days significantly reduced perceived stress, anxiety and fatigue compared to placebo.

Résultats

Multivitamin/mineral supplements can improve stress, fatigue and mood in healthy people.

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Illustration of the Fibriotics® study

Fibriotics®

Description

This randomized interventional study conducted by researchers at Stanford University assesses the impact of two diets targeting the gut microbiota, high in plant fibers or high in fermented foods, on microbiota composition and immune status in healthy adults.

Résultats

By combining these two complementary levers, Fibriotics® acts at the heart of the gut ecosystem to support the balance and vitality of the microbiota.

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Illustration of the study on Fibregum™ acacia fibers

Acacia fibers Fibregum™

Description

This study assesses the impact of arabinogalactan (AG, found in onely's Fibregum™ acacia fibers) on intestinal barrier function using an in vitro model simulating the human gut microbial ecosystem (SHIME).

Résultats

These results indicate that AG prebiotic fibers improve intestinal barrier function by modulating microbial fermentation along the colon.

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Illustration of the Reggenerate® study

Reggenerate®

Description

This in vitro study showed that eggshell membrane stimulates the expression of the AQP1 (responsible for water transport) and SIRT6 (involved in DNA repair and cellular longevity) genes.

Résultats

Reggenerate® eggshell membrane may promote anti-aging cellular mechanisms.

AQP1 gene expression multiplied by 3 vs control explant
SIRT6 gene expression multiplied by 1.7 vs control explant
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Illustration of the clinical study on Reggenerate™ eggshell membrane

Eggshell membrane Reggenerate™

Description

This randomized, double-blind, placebo-controlled clinical study evaluated the effect of a daily oral supplementation of 300 mg of eggshell membrane for 60 days in 50 adults (45–75 years) on skin parameters related to aging.

Résultats

Oral supplementation with eggshell membrane significantly improves several clinical signs of skin aging.

-18.7% transcutaneous water loss
+25% elasticity
+51.1% firmness after 60 days
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Eggshell membrane Reggenerate™

Description

In a randomized double-blind clinical study, 16 healthy volunteers with impaired skin barrier function took 300 mg of eggshell membrane or a placebo daily for 60 days.

Résultats

Oral supplementation with eggshell membrane restores the skin's barrier function and improves its biomechanical properties in people with skin alterations.

+65% and +35% for elasticity and skin fatigue
-43% transepidermal water loss
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Ginseng

Description

This scientific review summarizes current knowledge on the effects of Panax ginseng on the immune system, describing how its bioactive components influence both innate and adaptive immunity.

Résultats

Panax ginseng naturally strengthens the immune defenses thanks to ginsenosides.

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Illustration of the study on the bioavailability of CavaQ10®

CavaQ10®

Description

In an open-label crossover trial in 22 healthy adults, researchers compared absorption after a single oral dose of coenzyme Q10 (30 mg) in the form of a complex with γ-cyclodextrin.

Résultats

Complexing coenzyme Q10 with γ-cyclodextrin significantly increases the absorption and oral bioavailability of CoQ10 in healthy adults.

CavaQ10® is 18 times more bioavailable than standard CoQ10
View study

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