This randomised, double-blind, placebo-controlled clinical study on 300 mg of Metabolaid®, a polyphenol blend (extracts of lemon verbena and hibiscus), was carried out in 61 overweight people for 90 days to assess its effects on weight management, fat mass, satiety, and certain metabolic parameters.

The main results of this study show a significant reduction in body weight (around −2.8 to −3 kg, i.e. −3.4%), a decrease in fat mass (up to −8.2%), as well as improved satiety after meals, observed over 12 weeks.

This randomised, double-blind, placebo-controlled clinical study on 500 mg of Metabolaid®, a polyphenol blend (extracts of Lippia citriodora and Hibiscus sabdariffa), was carried out in 56 overweight or obese people for 8 weeks to assess its effects on weight, body composition, and cardiovascular and metabolic parameters.

The main results of this study show, in overweight people, a significant reduction in waist circumference (up to −6.8 cm) and fat mass (−3%), observed over 8 weeks with no change in diet or physical activity.

This randomised, double-blind, placebo-controlled clinical study on 500 mg of Metabolaid®, a polyphenol blend derived from lemon verbena and hibiscus, was carried out in 54 people for 8 weeks to assess its effects on weight management and body shape, as well as on satiety signals, particularly via GLP-1.

The main results of this study show an improvement in body measurements (weight, waist circumference and fat mass), associated with an increase in GLP-1, contributing to better satiety, reduced feelings of hunger and fewer snacking cravings, observed over 8 weeks.

This in vitro study assessed the effects of Metabolaid® on gut microbiota balance and the production of beneficial metabolites. Analyses were carried out using human microbiota under simulated conditions to observe interactions between polyphenols and the intestinal environment.

The results show that this polyphenol combination supports microbiota balance, with an increase in certain bacteria associated with good digestive function. It also stimulates the production of fermentation-derived compounds, including short-chain fatty acids such as butyrate.

This randomised, double-blind, placebo-controlled clinical study on 500 mg of Metabolaid®, a polyphenol blend derived from lemon verbena (325 mg) and hibiscus (175 mg), was carried out in 84 overweight people for 12 weeks to assess its effects on weight, body composition, and the mechanisms involved in energy management and satiety.

The main results of this study show a significant reduction in weight, BMI and fat mass, particularly abdominal fat, observed over 12 weeks.

Body composition analysis (in particular via the measurements shown in Figure 4) highlights a reduction in fat mass of up to around −6.9%, while preserving muscle mass.

This randomised, double-blind, placebo-controlled clinical study on 500 mg of polyphenols was carried out in 54 overweight people for 8 weeks to assess the effects of Metabolaid® on appetite, satiety, and signals associated with the regulation of food intake.

The main results of this study show a significant increase in satiety, associated with a rise in GLP-1, contributing to better appetite regulation.

These effects translate into reduced feelings of hunger and fewer snacking cravings, observed over 8 weeks, helping you manage your daily food intake more effectively.

This randomised, double-blind, placebo-controlled clinical study on 500 mg of polyphenols was carried out in 75 people for 12 weeks to assess the effects of Metabolaid® on eating behaviours, calorie intake and weight management, with a digitised tracking of daily habits.

The main results of this study show an improvement in eating behaviour, with reduced calorie intake and better regulation of food intake throughout the day.

These effects are accompanied by reductions in weight and fat mass, observed over 12 weeks, suggesting an overall impact on energy balance and intake control.

This randomised, double-blind, placebo-controlled clinical study on 30 mg of Safr’Inside™ saffron extract was carried out in 56 adults experiencing mild emotional discomfort for 8 weeks to assess its effects on wellbeing, emotional balance and stress response.

The main results of this study show improved emotional balance, with reduced negative feelings and improved quality of life—especially in social relationships—observed over 8 weeks.

Better adaptation to stress was also observed, with a more stable physiological response in stressful situations.

This randomised, double-blind, placebo-controlled, cross-over clinical study on 30 mg of saffron extract (Safr’Inside™) was carried out in 19 healthy men to assess its acute effects on stress response, measured through both physiological markers (cortisol) and subjective feelings during a standardised stress test.

The main results of this study show reduced perceived stress and anxiety after taking saffron, along with modulation of the physiological stress response.

In particular, the cortisol peak is delayed after taking saffron, indicating better adaptation of the body to a stressful situation.

This randomised, double-blind, placebo-controlled, cross-over clinical study on a saffron extract was carried out in 60 people for 8 weeks on snacking and cravings.

Reduced cravings and snacking

The study showed a reduction in cravings and snacking, and significant weight loss thanks to saffron compared with the placebo group.