Vitamin B9 Quatrefolic® (5MTHF-glucosamine)

Quatrefolic® is a patented fourth-generation folate developed by Gnosis. It is the glucosamine salt of 5-methyltetrahydrofolate (5-MTHF), the biologically active form of vitamin B9. Unlike conventional synthetic folic acid, Quatrefolic® requires no enzymatic conversion to be used by the body, making it directly bioavailable — including for individuals with genetic variations in the MTHFR gene that limit this conversion. Folate contributes to normal homocysteine metabolism, normal amino acid synthesis, and the normal formation of blood cells. It also plays a role in the process of cell division and contributes to normal psychological function. For women of childbearing age, adequate folate intake contributes to maternal tissue growth during pregnancy. Supplementing with Quatrefolic® is particularly relevant for people whose absorption or conversion of standard folate is reduced. Its high bioavailability and stability make it a reference option for meeting vitamin B9 needs in an effective and reliable way.